Article
A modeling approach to the self-assembly of the Golgi apparatus.
Biophysical journal - 16 Jun 2010
Kühnle Jens, Shillcock Julian, Mouritsen Ole G, Weiss Matthias
Abstract excerpt
The dynamic compartmentalization of eukaryotic cells is a fascinating phenomenon that is not yet understood. A prominent example of this challenge is the Golgi apparatus, the central hub for protein sorting and lipid metabolism in the secretory pathway. Despite major advances in elucidating its molecular biology, the fundamental question of how the morphogenesis of this organelle is organized on a system level...
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