Article
Genetic and functional study of the IPO5 gene in schizophrenia.
Psychiatry research - 30 May 2011
Wang Zhen-Qi, Liu Yang, Wu Ning, Xu Qi, Jin Shun-Zi, Ju Gui-Zhi, Ye Lin, Liu Li-Bo, Zhang Xuan, Wu Jiang
Abstract excerpt
The present work reported on a weak association of the importin 5 (IPO5) gene with schizophrenia in combined family and case-control samples and also investigated a possible mechanism by which the IPO5 gene may contribute to the development of the disease in a Chinese population. Our results suggest that abnormal expression and alternative splicing of the IPO5 gene may be involved in the pathophysiology of...
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