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Article

Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis

3 Jun 2010

Abstract excerpt

BACKGROUND: Most cancers maintain telomeres by activating telomerase but a significant minority, mainly of mesenchymal origin, utilize an alternative lengthening of telomeres (ALT) mechanism. METHODS: In this study we comparatively analyzed the prognostic relevance of ALT in a monoinstitutional series of 85 liposarcoma patients as a function of the marker (ALT-associated promyelocytic leukemia bodies (APB) versus...

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Share to Nuclear Structure and Function
Share to Retinoids in leukemia and cellular processes
Share to Telomeres, Telomerase, and Senescence

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PMID: 20525266
DOI: 10.1186/1471-2407-10-254

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