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Article

Molecularly genetic analysis of von Hippel-Lindau associated central nervous system hemangioblastoma

12 Apr 2010

Abstract excerpt

Von Hippel-Lindau (VHL) disease is an autosomal dominant inherited cancer predisposition syndrome, characterized by development of a variety of neoplasms in multiple organs. Central nervous system hemangioblastoma (CHB) is the most common manifestation of VHL disease. The germline mutations in the VHL tumor suppressor gene are responsible for the inherited cancer predisposition syndrome. To expand the VHL...

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PMID: 20518900
DOI: 10.1111/j.1440-1827.2010.02540.x

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