Novel Mechanism of Fetal Hepatocyte Injury in Congenital Alloimmune Hepatitis Involves the Terminal Complement Cascade

doi:10.1002/hep.23581

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Novel Mechanism of Fetal Hepatocyte Injury in Congenital Alloimmune Hepatitis Involves the Terminal Complement Cascade

3 Feb 2010

Abstract excerpt

UNLABELLED: Evidence suggests that most neonatal hemochromatosis (NH) is the phenotypic expression of gestational alloimmune fetal liver injury. Gestational alloimmune diseases are induced by the placental passage of specific reactive immunoglobulin G and often involve the activation of fetal complement by the classical pathway leading to the formation of membrane attack complex (MAC) as the effector of cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Iron Metabolism and Disorders
Share to Liver Diseases and Immunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed

Identifiers

PMID: 20512994
DOI: 10.1002/hep.23581

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Novel Mechanism of Fetal Hepatocyte Injury in Congenital Alloimmune Hepatitis Involves the Terminal Complement CascadePMID 20512994Read ↗

[Neonatal hemochromatosis: a neonate alloimmune disease].Semantic proximity Read ↗

Gestational Alloimmune Liver Disease in Cases of Fetal DeathSemantic proximity Read ↗

Neonatal hepatitis syndrome.Semantic proximity Read ↗

Pathology teach and tell: neonatal hemochromatosis with massive hepatic necrosis.Semantic proximity Read ↗

Neonatal hemochromatosis.Semantic proximity Read ↗

Maternal microchimerism in underlying pathogenesis of biliary atresia: quantification and phenotypes of maternal cells in the liver.Semantic proximity Read ↗

The complement system and adverse pregnancy outcomes.Semantic proximity Read ↗

Fetal liver development and implications for liver disease pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.