Article
Minor histocompatibility antigen HA-1 and HA-2 polymorphisms in Taiwan: frequency and application in hematopoietic stem cell transplantation.
Clinical chemistry and laboratory medicine - 1 Sept 2010
Lio Hoi-Yan, Tang Jih-Luh, Wu Jui, Wu Shang-Ju, Lin Chun-Ying, Yang Ya-Chien
Abstract excerpt
BACKGROUND: Minor histocompatibility antigens influence the occurrence of graft-vs.-host disease and graft-vs.-leukemia effects after hematopoietic stem cell transplantation (HSCT). We determined the population frequencies of HA-1 and HA-2 alleles in Taiwan and exploited their potential applications in allogeneic HSCT. METHODS: HA-1 and HA-2 were genotyped using polymerase chain reaction and restriction fragment...
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