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Article

Separation of clonogenic and differentiated cell phenotypes of ovarian cancer cells (HOC-7) by discontinuous density gradient centrifugation.

Cancer letters - 14 Jun 1991

Grunt T W, Dittrich E, Somay C, Wagner T, Dittrich C

Abstract excerpt

We isolated clonogenic cells from differentiated HOC-7 ovarian cancer cells. Both cell subsets were characterised in respect to morphology, growth behaviour, DNA content and expression of tumour-associated antigens and nuclear oncogenes. Ten cell fractions (Fr) were separated by centrifugation in...

Topics

Antigens, Tumor-Associated, Carbohydrate
Cell Differentiation
Cell Division
Cell Line
Cell Separation
Centrifugation, Density Gradient
Clone Cells
DNA, Neoplasm
Female
Flow Cytometry
Humans
Ovarian Neoplasms

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Identifiers

PMID: 2049785
DOI: 10.1016/0304-3835(91)90018-d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2049785-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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