Article
Aortic abnormalities in males with Alport syndrome.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2010
Kashtan Clifford E, Segal Yoav, Flinter Frances, Makanjuola David, Gan Jay-Sen, Watnick Terry
Abstract excerpt
BACKGROUND: There have been isolated case reports of arterial disease in males with Alport syndrome (AS), a systemic disorder of Type IV collagen. In this paper, we describe five new cases of AS associated with significant aortic disease including dissection and aneurysm. METHODS: We present brief clinical descriptions of five males with AS and aortic disease. We performed immunohistochemical analysis of the...
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