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Improving FISH diagnosis for preimplantation genetic aneuploidy screening

19 May 2010

Abstract excerpt

BACKGROUND: In our routine programme of preimplantation genetic aneuploidy screening (PGS) by fluorescence in situ hybridization (FISH), nine chromosomes (13, 15, 16, 17, 18, 21, 22, X and Y) are analysed in two consecutive hybridization rounds. We also perform additional hybridization rounds for these chromosomes, using probes that bind to different loci, for non-conclusive results and for confirmation of...

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Share to Genetic Syndromes and Imprinting
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PMID: 20488802
DOI: 10.1093/humrep/deq122

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