Article
Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in Idiopathic Pulmonary Fibrosis (IPF).
Respiratory medicine - 1 Oct 2010
Antoniou Katerina M, Papadaki Helen A, Soufla Giannoula, Kastrinaki Maria Christina, Damianaki Athina, Koutala Helen, Spandidos Demetrios A, Siafakas Nikolaos M
Abstract excerpt
BACKGROUND: Experimental data have provided evidence that progenitor cells of bone marrow (BM) origin may play a role in the fibrogenic process of the lung. OBJECTIVE: To probe the possible involvement of BM mesenchymal stem cells (MSCs) in the pathophysiology of Idiopathic Pulmonary Fibrosis (IPF) by investigating the molecular profile of these cells. DESIGN: BM MSCs were studied in 10 IPF patients and 10...
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