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Article

Genes Associated With Alcohol Abuse and Tobacco Smoking in the Human Nucleus Accumbens and Ventral Tegmental Area

5 May 2010

Abstract excerpt

BACKGROUND: The incidence of alcohol and tobacco co-abuse is as high as 80%. The molecular mechanism underlying this comorbidity is virtually unknown, but interactions between these drugs have important implications for the development of and recovery from drug dependence. METHODS: We investigated the effects of chronic tobacco and alcohol abuse and the interaction of the 2 behaviors on global gene expression in...

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PMID: 20477762
DOI: 10.1111/j.1530-0277.2010.01207.x

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