Article
In vitro antibacterial activities of S-013420, a novel bicyclolide, against respiratory tract pathogens.
The Journal of antimicrobial chemotherapy - 1 Jul 2010
Homma Tomoyuki, Fujimura Takaji, Maki Hideki, Yamano Yoshinori, Shimada Jingoro, Kuwahara Shogo
Abstract excerpt
OBJECTIVES: The in vitro activity of S-013420, a novel bicyclolide, was investigated. METHODS: All test strains for this study were isolated from Japanese medical facilities. MICs were determined by the microbroth dilution method or agar dilution method according to the CLSI guidelines. In time-kill kinetics, viable cells were measured at 1, 2.5, 4 and 6 h after exposure to antimicrobials. The frequencies of...
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