Article
The case for routine genotyping in dual-antiplatelet therapy.
Journal of the American College of Cardiology - 6 Jul 2010
Damani Samir B, Topol Eric J
Abstract excerpt
Over 1 million coronary stent procedures are performed annually in the U.S., with dual-antiplatelet therapy, which includes the use of both aspirin and clopidogrel, being a cornerstone in the management of these patients after coronary intervention. Now, recent data have surfaced demonstrating altered active metabolite levels of clopidogrel in patients harboring hepatic cytochrome gene variants. These variants,...
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