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Article

Maternal-zygotic epistasis and the evolution of genetic diseases.

Journal of biomedicine & biotechnology - 1 Jan 2010

Priest Nicholas K, Wade Michael J

Abstract excerpt

Many birth defects and genetic diseases are expressed in individuals that do not carry the disease causing alleles. Genetic diseases observed in offspring can be caused by gene expression in mothers and by interactions between gene expression in mothers and offspring. It is not clear whether the underlying pattern of gene expression (maternal versus offspring) affects the incidence of genetic disease. Here we...

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Identifiers

PMID: 20467476
DOI: 10.1155/2010/478732
PMCID: PMC2867001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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