Article
Determination of isoleucine side-chain conformations in ground and excited states of proteins from chemical shifts.
Journal of the American Chemical Society - 9 Jun 2010
Hansen D Flemming, Neudecker Philipp, Kay Lewis E
Abstract excerpt
A simple method is presented for quantifying Ile chi(2) rotamer distributions in proteins based on the measurement of Ile (13)C(delta1) chemical shifts. The methodology is well suited for applications involving very high molecular weight protein complexes, where other NMR parameters such as side-...
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