Article
Quantitative trait analysis suggests human DAZL may be involved in regulating sperm counts and motility.
Reproductive biomedicine online - 1 Jul 2010
Hsu Chao-Chin, Kuo Po-Hsiu, Lee I-Wen, Su Mei-Tsz, Tseng Joseph T, Kuo Pao-Lin
Abstract excerpt
A prospective study was carried out to identify the association of the DAZL (deleted in azoospermia-like) gene with major semen parameters in 210 men with normal and 467 men with abnormal semen parameters. Primer extension analysis for single nucleotide polymorphisms (SNP) of DAZL and quantitative trait analysis on the association of allele/genotype frequencies, linkage disequilibrium characteristics and DAZL...
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