Article
Atheromatosis extent in coronary artery disease is not correlated with apolipoprotein-E polymorphism and its plasma levels, but associated with cognitive decline.
Current Alzheimer research - 1 Sept 2010
Lima L M, Carvalho M d G, Ferreira C N, Fernandes A P, Neto C P d F, Garcia J C F, Reis H J, Janka Z, Palotás A, Sousa M d O
Abstract excerpt
BACKGROUND: Apolipoprotein-E (apoE) ε4 allele is a known risk factor for Alzheimer's disease (AD). Polymorphism of apoE is also one of the most important genetic markers for coronary artery disease (CAD). The allelic variation in the apoE gene has a significant effect on inter-individual variation of lipids and lipoprotein plasma levels as well. This study investigated whether apoE polymorphism affects the plasma...
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