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Article

BMP-2 and FGF-2 synergistically facilitate adoption of a cardiac phenotype in somatic bone marrow c-kit+/Sca-1+ stem cells.

Clinical and translational science - 1 Sept 2008

Degeorge Brent R, Rosenberg Marc, Eckstein Volker, Gao Erhe, Herzog Nicole, Katus Hugo A, Koch Walter J, Frey Norbert, Most Patrick

Abstract excerpt

The aim of this study was to explore the effect of bone morphogenetic protein-2 (BMP-2) and fibroblast growth factor-2 (FGF-2)- paracrine factors implicated in both cardiac embryogenesis and cardiac repair following myocardial infarction (MI)-on murine bone marrow stem cell (mBMSC) differentiation in an ex vivo cardiac microenvironment. For this purpose, green fluorescent protein (GFP) expressing hematopoietic...

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Identifiers

PMID: 20443832
DOI: 10.1111/j.1752-8062.2008.00034.x
PMCID: PMC2863128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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