Article
Administration of ondansetron is associated with lethal outcome.
Pediatrics - 1 Jun 2010
Gener Blanca, Burns Jarrett M, Griffin Susanne, Boyer Edward W
Abstract excerpt
We report here the case of a child with a known muscular abnormality and susceptibility to malignant hyperthermia who abruptly died after receiving a therapeutic dose of ondansetron. Also, we discuss the pharmacodynamic relationship of ondansetron to malignant hyperthermia in a susceptible host.
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