Article
Explosive HIV-1 subtype B' epidemics in Asia driven by geographic and risk group founder events.
Virology - 5 Jul 2010
Li Yue, Uenishi Rie, Hase Saiki, Liao Huanan, Li Xiao-Jie, Tsuchiura Takayo, Tee Kok Keng, Pybus Oliver G, Takebe Yutaka
Abstract excerpt
We explored the timescale, spatial spread, and risk group population structure of HIV-1 subtype B', the cause of explosive blood-borne HIV-1 epidemics among injecting drug users (IDUs) and former plasma donors (FPDs) in Asia. Sequences from FPDs in China formed a distinct monophyletic cluster within subtype B'. Further analysis revealed that subtype B' was founded by a single lineage of pandemic subtype B around...
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