Article
Antibody reactivity to deletion mutants of the HIV-1 SF2 envelope.
Intervirology - 1 Jan 1991
Back N K, Haigwood N L, de Wolf F, de Jongh B M, Goudsmit J
Abstract excerpt
In human immunodeficiency virus type 1 (HIV-1) infected individuals, the antibody response to the external envelope (gp120) is associated with in vitro neutralization. To further characterize the anti-gp120 response, we examined the IgG reactivity of 75 HIV-1-seroconverted and 200 HIV-1-seropositive individuals to deletion mutants of gp120 in an enzyme immunoassay. We used yeast-derived, non-glycosylated...
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