Intravenous immunoglobulin treatment in multifocal motor neuropathy.

doi:10.1007/s10875-010-9408-3

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Article

Intravenous immunoglobulin treatment in multifocal motor neuropathy.

Journal of clinical immunology - 1 May 2010

van der Pol W-Ludo, Cats Elisabeth A, van den Berg Leonard H

Abstract excerpt

INTRODUCTION: Multifocal motor neuropathy (MMN) is characterized by asymmetric weakness of limbs and the electrophysiological finding of conduction block in motor nerves. Conduction block is the inability of nerves to propagate action potentials and is probably caused by immune-mediated dysfunction of the axon at the nodes of Ranvier or the myelin sheath. MMN immune pathogenesis has not been elucidated. RESULTS:...

Topics

Adult
Aged
Autoantibodies
Autoantigens
Autoimmune Diseases of the Nervous System
Female
Forecasting
G(M1) Ganglioside
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Immunoglobulin M
Immunoglobulins, Intravenous
Male
Middle Aged
Motor Neuron Disease
Neural Conduction

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Identifiers

PMID: 20405181
DOI: 10.1007/s10875-010-9408-3
PMCID: PMC2883087

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