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Article

Sequencing and genetic variation of multidrug resistance plasmids in Klebsiella pneumoniae.

PloS one - 12 Apr 2010

Zhao Fangqing, Bai Jie, Wu Jinyu, Liu Jing, Zhou Mingming, Xia Shilin, Wang Shanjin, Yao Xiaoding, Yi Huiguang, Lin Meili, Gao Shengjie, Zhou Tieli, Xu Zuyuan, Niu Yuxin, Bao Qiyu

Abstract excerpt

BACKGROUND: The development of multidrug resistance is a major problem in the treatment of pathogenic microorganisms by distinct antimicrobial agents. Characterizing the genetic variation among plasmids from different bacterial species or strains is a key step towards understanding the mechanism of virulence and their evolution. RESULTS: We applied a deep sequencing approach to 206 clinical strains of Klebsiella...

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Share to Base Sequence
Share to Conjugation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Genetic Variation

Share to Klebsiella pneumoniae

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Share to Selection, Genetic

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 20405037
DOI: 10.1371/journal.pone.0010141
PMCID: PMC2853573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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