Article
Monoclonal antibodies in the treatment of metastatic colorectal cancer: a review.
Clinical therapeutics - 1 Mar 2010
Tol Jolien, Punt Cornelis J A
Abstract excerpt
BACKGROUND: Two groups of agents targeting either the vascular endothelial growth factor (VEGF) receptor or the epidermal growth factor receptor (EGFR) have been added to the therapeutic arsenal against metastatic colorectal cancer (mCRC). Currently available agents in these groups are the anti-VEGF antibody bevacizumab and the anti-EGFR antibodies cetuximab and panitumumab. OBJECTIVES: This article reviews the...
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