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Article

Evolution of highly pathogenic avian H5N1 influenza viruses and the emergence of dominant variants.

The Journal of general virology - 1 Aug 2010

Neumann Gabriele, Green Margaret A, Macken Catherine A

Abstract excerpt

Highly pathogenic avian H5N1 viruses have circulated in South-east Asia for more than a decade and have now spread to more than 60 countries. The evolution of these viruses is characterized by frequent reassortment of the so-called 'internal' genes, creating novel genotypes. Additionally, over time, the surface glycoprotein, haemagglutinin (HA), which is the primary target of the adaptive immune response, has...

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PMID: 20392897
DOI: 10.1099/vir.0.020750-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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