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Researching genetic versus nongenetic determinants of disease: a comparison and proposed unification.

Science translational medicine - 18 Nov 2009

Ioannidis John P A, Loy En Yun, Poulton Richie, Chia Kee Seng

Abstract excerpt

Research standards deviate in genetic versus nongenetic epidemiology. Besides some immutable differences, such as the correlation pattern between variables, these divergent research standards can converge considerably. Current research designs that dissociate genetic and nongenetic measurements are reaching their limits. Studies are needed that massively measure genotypes, nongenetic exposures, and outcomes...

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PMID: 20368180
DOI: 10.1126/scitranslmed.3000247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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