Article
[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].
Zhonghua yi xue za zhi - 26 Jan 2010
Tan Yu-Yu, Lin Jian, Huang Gan, Tang Wei-Li, Sedimbi Saikiran K, Sanjeevi Carani B, Zhou Zhi-Guang
Abstract excerpt
OBJECTIVE: To investigate the association of Killer cell immunoglobin-like receptor (KIR) gene and KIRs'ligand (HLA-C) gene polymorphisms with type 1 diabetes (T1DM). METHODS: Using polymerase chain reaction-sequence specific primer (PCR-SSP) to detect KIR and HLA-C genotype in 180 T1DM patients and 199 healthy controls from Hunan Han population. RESULTS: (1) The frequencies of KIR 2DL1 (98.9% vs 92.0%, OR =...
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