Article
Viral protein expression and phenotyping of inflammatory responses in the central nervous system of phocine distemper virus-infected harbor seals (Phoca vitulina).
Veterinary microbiology - 28 Sept 2010
Stimmer Lev, Siebert Ursula, Wohlsein Peter, Fontaine Jean-Jacques, Baumgärtner Wolfgang, Beineke Andreas
Abstract excerpt
The central nervous system (CNS) represents an important target organ of the phocine distemper virus (PDV). The aim of the present study was to characterize pathological changes in the CNS of harbor seals suffering from natural PDV-infection. The distribution of virus protein and mRNA was investigated by immunohistochemistry (IHC) and in situ hybridization, respectively. In addition, inflammatory and glial cells...
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