Article
Emergence of canine distemper virus strains with modified molecular signature and enhanced neuronal tropism leading to high mortality in wild carnivores.
Veterinary pathology - 1 Nov 2012
Origgi F C, Plattet P, Sattler U, Robert N, Casaubon J, Mavrot F, Pewsner M, Wu N, Giovannini S, Oevermann A, Stoffel M H, Gaschen V, Segner H, Ryser-Degiorgis M-P
Abstract excerpt
An ongoing canine distemper epidemic was first detected in Switzerland in the spring of 2009. Compared to previous local canine distemper outbreaks, it was characterized by unusually high morbidity and mortality, rapid spread over the country, and susceptibility of several wild carnivore species. Here, the authors describe the associated pathologic changes and phylogenetic and biological features of a multiple...
Topics
- Amino Acid Substitution
- Animals
- Animals, Domestic
- Animals, Wild
- Base Sequence
- Carnivora
- Cell Line
- Disease Outbreaks
- Distemper
- Distemper Virus, Canine