Article
[Effect of mutations in Drosophila melanogaster tumor suppressor Merlin on proliferation and differentiation of wing cells].
Genetika - 1 Feb 2010
Dubatolova T D, Kopyl S A, Bulgakova N A, Dorogova N V, Omel'ianchuk L V, Chang L -Sh
Abstract excerpt
Experiments on transplantation of wing imaginal discs homozygous for a mutation in the tumor suppressor gene Merlin have demonstrated that this mutation does not induce malignant tumors. Marking of the wing disc compartment borders by specific antibodies showed the absence of essential compartment border defects in case of the Merlin mutation. Drosophila melanogaster cells mutant for Merlin have shorter cell...
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