Article
ProbABEL package for genome-wide association analysis of imputed data.
BMC bioinformatics - 16 Mar 2010
Aulchenko Yurii S, Struchalin Maksim V, van Duijn Cornelia M
Abstract excerpt
BACKGROUND: Over the last few years, genome-wide association (GWA) studies became a tool of choice for the identification of loci associated with complex traits. Currently, imputed single nucleotide polymorphisms (SNP) data are frequently used in GWA analyzes. Correct analysis of imputed data calls for the implementation of specific methods which take genotype imputation uncertainty into account. RESULTS: We...
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