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Article

Association of the OCA2 polymorphism His615Arg with melanin content in east Asian populations: further evidence of convergent evolution of skin pigmentation.

PLoS genetics - 5 Mar 2010

Edwards Melissa, Bigham Abigail, Tan Jinze, Li Shilin, Gozdzik Agnes, Ross Kendra, Jin Li, Parra Esteban J

Abstract excerpt

The last decade has witnessed important advances in our understanding of the genetics of pigmentation in European populations, but very little is known about the genes involved in skin pigmentation variation in East Asian populations. Here, we present the results of a study evaluating the association of 10 Single Nucleotide Polymorphisms (SNPs) located within 5 pigmentation candidate genes (OCA2, DCT, ADAM17,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20221248
DOI: 10.1371/journal.pgen.1000867
PMCID: PMC2832666

Genes

OCA2
ADAM17
ADAMTS20
DCT
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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