Article
Influence of genotype on the natural history of untreated proliferative sickle retinopathy--an angiographic study.
The British journal of ophthalmology - 1 Apr 1991
Fox P D, Vessey S J, Forshaw M L, Serjeant G R
Abstract excerpt
The natural history of untreated proliferative sickle retinopathy (PSR) has been observed in 35 patients (40 eyes) with homozygous sickle cell (SS) disease and in 112 patients (114 eyes) with sickle cell-haemoglobin C (SC) disease over a mean follow-up period of 4.5 years (range 0.5-14.0 years). In both genotypes progression of PSR was most frequent between ages 20 and 39 years. Spontaneous regression was more...
Topics
- Adolescent
- Adult
- Age Factors
- Anemia, Sickle Cell
- Female
- Genotype
- Hemoglobin SC Disease
- Humans
- Male
- Middle Aged
- Radiography
- Retinal Diseases