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Expression Levels of the microRNA Processing Enzymes Drosha and Dicer in Epithelial Skin Cancer

8 Mar 2010

Abstract excerpt

BACKGROUND: Dysregulation of microRNA (miRNA) metabolism has been observed in a variety of human cancers. In this pilot study, we investigated expression profiles of the two most important enzymes of the miRNA machinery, Drosha and Dicer, in relation to epithelial skin cancer and its premalignant stage. METHODS: Patients with premalignant actinic keratoses (AK, n = 6), basal cell carcinomas (BCC, n = 15), and...

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PMID: 20210522
DOI: 10.3109/07357901003630918

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