Article
[Influential factors of Hardy-Weinberg equilibrium on the study of association between gene polymorphism and disease].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Nov 2009
Chen A-qun, Zang Jing, Feng Yun-xia, Wang Kai-juan
Abstract excerpt
OBJECTIVE: According to the data collected from gastric cancer families comparative study, the influence factors of Hardy-Weinberg (H-W) equilibrium in the association studies of gene polymorphism and disease were analyzed to reveal the reasons that affecting the equilibrium deviation in the group. METHODS: Varieties of risk genotype for gastric cancer were analyzed and detected with H-W equilibrium, genetic...
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