Article
Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21).
The Journal of biological chemistry - 30 Apr 2010
Lampl Nardy, Budai-Hadrian Ofra, Davydov Olga, Joss Tom V, Harrop Stephen J, Curmi Paul M G, Roberts Thomas H, Fluhr Robert
Abstract excerpt
In animals, protease inhibitors of the serpin family are associated with many physiological processes, including blood coagulation and innate immunity. Serpins feature a reactive center loop (RCL), which displays a protease target sequence as a bait. RCL cleavage results in an irreversible, coval...
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