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Dermatoses affecting desmosomes in animals: a mechanistic review of acantholytic blistering skin diseases

1 Oct 2009

Abstract excerpt

Failure of desmosomal adhesion with ensuing keratinocyte separation - a phenomenon called acantholysis - can result from genetic, autoimmune or infectious proteolytic causes. Rare hereditary disorders of desmosomal formation have been identified in animals. Familial acantholysis of Angus calves and hereditary suprabasal acantholytic mechanobullous dermatosis of buffaloes appear to be similar to acantholytic...

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PMID: 20178467
DOI: 10.1111/j.1365-3164.2009.00821.x

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