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Article

The risk of Parkinson's disease in type 1 Gaucher disease.

Journal of inherited metabolic disease - 1 Apr 2010

Bultron Gilberto, Kacena Katherine, Pearson Daniel, Boxer Michael, Yang Ruhua, Sathe Swati, Pastores Gregory, Mistry Pramod K

Abstract excerpt

In Gaucher disease, defective lysosomal glucocerebrosidase due to mutations in the GBA1 gene results in lysosomal accumulation of glucocerebroside in mononuclear phagocytes and a multisystemic phenotype. Observations of occurrence of Parkinson's disease in some patients with non-neuronopathic typ...

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Source

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Identifiers

PMID: 20177787
DOI: 10.1007/s10545-010-9055-0
PMCID: PMC2887303

Genes

GBA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20177787-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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