Article
Chlamydomonas mutants display reversible deficiencies in flagellar beating and axonemal assembly.
Cytoskeleton (Hoboken, N.J.) - 1 Feb 2010
Wei Mei, Sivadas Priyanka, Owen Heather A, Mitchell David R, Yang Pinfen
Abstract excerpt
Axonemal complexes in flagella are largely prepackaged in the cell body. As such, one mutation often results in the absence of the co-assembled components and permanent motility deficiencies. For example, a Chlamydomonas mutant defective in RSP4 in the radial spoke (RS), which is critical for bend propagation, has paralyzed flagella that also lack the paralogue RSP6 and three additional RS proteins. Intriguingly,...
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