Article
Comparison of breast cancer to healthy control tissue discovers novel markers with potential for prognosis and early detection.
PloS one - 9 Feb 2010
Schummer Michèl, Green Ann, Beatty J David, Karlan Beth Y, Karlan Scott, Gross Jenny, Thornton Sean, McIntosh Martin, Urban Nicole
Abstract excerpt
This study was initiated to identify biomarkers with potential value for the early detection of poor-outcome breast cancer. Two sets of well-characterized tissues were utilized: one from breast cancer patients with favorable vs. poor outcome and the other from healthy women undergoing reduction mammaplasty. Over 46 differentially expressed genes were identified from a large list of potential targets by a) mining...
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