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Article

Di-adenosine tetraphosphate (Ap4A) metabolism impacts biofilm formation by Pseudomonas fluorescens via modulation of c-di-GMP-dependent pathways.

Journal of bacteriology - 1 Jun 2010

Monds Russell D, Newell Peter D, Wagner Jeffrey C, Schwartzman Julia A, Lu Wenyun, Rabinowitz Joshua D, O'Toole George A

Abstract excerpt

Dinucleoside tetraphosphates are common constituents of the cell and are thought to play diverse biological roles in organisms ranging from bacteria to humans. In this study we characterized two independent mechanisms by which di-adenosine tetraphosphate (Ap4A) metabolism impacts biofilm formation by Pseudomonas fluorescens. Null mutations in apaH, the gene encoding nucleoside tetraphosphate hydrolase, resulted...

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Share to Biofilms
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic GMP

Share to Dinucleoside Phosphates

Share to Gene Expression Regulation, Bacterial

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Source

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Identifiers

PMID: 20154123
DOI: 10.1128/JB.01571-09
PMCID: PMC2901679

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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