Genotypic analysis of diffuse, mixed cell lymphomas. Comparison with morphologic and immunophenotypic findings.

doi:10.1093/ajcp/95.4.547

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genotypic analysis of diffuse, mixed cell lymphomas. Comparison with morphologic and immunophenotypic findings.

American journal of clinical pathology - 1 Apr 1991

Medeiros L J, Lardelli P, Stetler-Stevenson M, Longo D L, Jaffe E S

Abstract excerpt

Malignant lymphoma, diffuse, mixed small and large cell type, as defined in the Working Formulation, is heterogeneous both morphologically and immunophenotypically and, in some cases, clonality may be difficult to determine. Because gene rearrangement analysis has been shown to be a sensitive method for determining clonality, the authors genotyped 20 cases and compared the results with histologic and...

Topics

Adult
Aged
B-Lymphocytes
Blotting, Southern
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 18
DNA, Neoplasm
Female
Gene Rearrangement, T-Lymphocyte
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunophenotyping

Lymphoma, Non-Hodgkin

Male

Middle Aged

Polymerase Chain Reaction

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-bcl-2

Source

Open in PubMed

Identifiers

PMID: 2014781
DOI: 10.1093/ajcp/95.4.547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2014781-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Genotypic analysis of diffuse, mixed cell lymphomas. Comparison with morphologic and immunophenotypic findings.PMID 2014781Read ↗

Alterations of the p53 tumor suppressor gene in diffuse large cell lymphomas with translocations of the c-MYC and BCL-2 proto-oncogenes.Semantic proximity Read ↗

Immunohistochemistry and gene rearrangement studies in the diagnosis of malignant lymphomas: a comparison of 152 cases.Semantic proximity Read ↗

Genotypic analysis in large cell lymphomas expressing a restricted set of differentiation antigens.Semantic proximity Read ↗

Analysis of beta, gamma, and delta T-cell receptor genes in lymphomatoid papulosis: cellular basis of two distinct histologic subsets.Semantic proximity Read ↗

Chromosome abnormalities in malignant lymphoma in patients from Kurashiki: histological and immunophenotypic correlations.Semantic proximity Read ↗

Lymphoma with multi gene rearrangement on the level of immunoglobulin heavy chain, light chains, and T-cell receptor beta chain.Semantic proximity Read ↗

Combined analysis of T cell receptor gamma and immunoglobulin heavy chain gene rearrangements at the single-cell level in lymphomas with dual genotype.Semantic proximity Read ↗

Immunophenotyping of non-Hodgkin's lymphomas in paraffin-embedded tissue sections. A comparison with genotypic analysis.Semantic proximity Read ↗

Comparison of Cytogenetic Analysis, Southern Analysis, and Polymerase Chain Reaction for the Detection of t(14; 18) in Follicular LymphomaSemantic proximity Read ↗

Clonality of T cell and phenotypically undefined lymphoid neoplasms: the value of genotypic analyses.Semantic proximity Read ↗

A genotypic study of low grade B-cell lymphomas, including lymphomas of mucosa associated lymphoid tissue (MALT).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.