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Article

Testicular dysgenesis syndrome comprises some but not all cases of hypospadias and impaired spermatogenesis

4 Feb 2010

Abstract excerpt

In 2001, when the testicular dysgenesis syndrome (TDS) concept was proposed, it suggested that impaired development of foetal testes could lead to increased risks of cryptorchidism, hypospadias, decreased spermatogenesis or testis cancer. The TDS concept links the pathogenesis of the four disorders together, but does not imply that all affected men develop all four symptoms. The least affected men may merely have...

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PMID: 20132348
DOI: 10.1111/j.1365-2605.2009.01050.x

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