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Article

The molecular genetics of holoprosencephaly.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 Feb 2010

Roessler Erich, Muenke Maximilian

Abstract excerpt

Holoprosencephaly (HPE) has captivated the imagination of Man for millennia because its most extreme manifestation, the single-eyed cyclopic newborn infant, brings to mind the fantastical creature Cyclops from Greek mythology. Attempting to understand this common malformation of the forebrain in modern medical terms requires a systematic synthesis of genetic, cytogenetic, and environmental information typical for...

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Identifiers

PMID: 20104595
DOI: 10.1002/ajmg.c.30236
PMCID: PMC2815021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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