Article
Increased expression of collagens, transforming growth factor-beta1, and -beta3 in gluteal muscle contracture.
BMC musculoskeletal disorders - 25 Jan 2010
Zhao Chen-Guang, He Xi-Jing, Lu Bin, Li Hao-Peng, Kang An-Jing
Abstract excerpt
BACKGROUND: Gluteal muscle contracture (GMC) is a multi-factor human chronic fibrotic disease of the gluteal muscle. Fibrotic tissue is characterized by excessive accumulation of collagen in the muscle's extracellular matrix. Transforming growth factor (TGF)-beta1 and -beta2 are thought to play an important role in fibrogenesis, while TGF-beta3 is believed to have an anti-fibrotic function. We hypothesize that...
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