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Article

Genetics and molecular pathology of Stargardt-like macular degeneration.

Progress in retinal and eye research - 1 May 2010

Vasireddy Vidyullatha, Wong Paul, Ayyagari Radha

Abstract excerpt

Stargardt-like macular degeneration (STGD3) is an early onset, autosomal dominant macular degeneration. STGD3 is characterized by a progressive pathology, the loss of central vision, atrophy of the retinal pigment epithelium, and accumulation of lipofuscin, clinical features that are also characteristic of age-related macular degeneration. The onset of clinical symptoms in STGD3, however, is typically observed...

Topics

Animals
Chromosomes, Human, Pair 6
Eye Proteins
Fatty Acids
Humans
Macular Degeneration
Membrane Proteins
Mice
Mice, Transgenic
Models, Biological
Mutation
Pathology, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20096366
DOI: 10.1016/j.preteyeres.2010.01.001
PMCID: PMC3059896

Genes

ELOVL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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