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Article

Dominant connexin26 mutants associated with human hearing loss have trans-dominant effects on connexin30.

Neurobiology of disease - 1 May 2010

Yum Sabrina W, Zhang Junxian, Scherer Steven S

Abstract excerpt

Dominant mutations in GJB2, the gene encoding the human gap junction protein connexin26 (Cx26), cause hearing loss. We investigated whether dominant Cx26 mutants interact directly with Cx30. HeLa cells stably expressing nine dominant Cx26 mutants, six associated with non-syndromic hearing loss (W...

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Identifiers

PMID: 20096356
DOI: 10.1016/j.nbd.2010.01.010
PMCID: PMC2868926

Genes

GJB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20096356-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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