Article
Serum cholinesterase polymorphism in France: an epidemiological survey of the deficient alleles detected by an automated micro-method.
Annals of human biology - 1 Jan 2000
Arnaud J, Brun H, Llobera R, Constans J
Abstract excerpt
The polymorphism of the serum cholinesterase CHE 1 was determined using an automated micro-method. The procedure developed represents an improvement of the manual method and enabled us to study more than 2400 samples obtained in 15 different geographical areas in France. Four alleles were detected: CHE1* U, A, S and F. An exceptionally high frequency of an atypical variant (CHE1*A) was observed in the central...
Topics
- Adult
- Alleles
- Child
- Cholinesterases
- Clinical Enzyme Tests
- France
- Gene Frequency
- Humans
- Polymorphism, Genetic
- Succinylcholine
