Article
Genetic factors in bone turnover.
The Journal of clinical endocrinology and metabolism - 1 Apr 1991
Kelly P J, Hopper J L, Macaskill G T, Pocock N A, Sambrook P N, Eisman J A
Abstract excerpt
Genetic factors are major determinants of adult bone density, however, it is unknown how these effects may be mediated. Since bone mineral density is the net result of bone formation and bone resorption we studied biochemical indices of bone formation (serum osteocalcin) and resorption [fasting urinary calcium:creatinine (Ca/Crt) and hydroxyproline:creatinine (OH/Crt)] in adult female twins; 39 monozygotic (MZ)...
Topics
- Adult
- Aged
- Bone Density
- Creatine
- Female
- Genetic Variation
- Humans
- Hydroxyproline
- Middle Aged
- Models, Biological
- Osteocalcin
- Twins, Dizygotic