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Second lineage of heart forming region provides new understanding of conotruncal heart defects

24 Dec 2009

Abstract excerpt

Abnormal heart development causes various congenital heart defects. Recent cardiovascular biology studies have elucidated the morphological mechanisms involved in normal and abnormal heart development. The primitive heart tube originates from the lateral-most part of the heart forming mesoderm and mainly gives rise to the left ventricle. Then, during the cardiac looping, the outflow tract is elongated by the...

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PMID: 20050864
DOI: 10.1111/j.1741-4520.2009.00267.x

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